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Peripheral Blood Flow

The peripheral blood flow or microcirculation parameter is well known and well researched, see links below for a sampling of literature articles in a variety of acute and chronic care applications:

Critical Care: Microcirculation Function

Microcirculatory function monitoring at the bedside--a view from the intensive care. Knotzer H1, Hasibeder WR., Physiol Meas. 2007 Sep;28(9):R65-86. Epub 2007 Aug 21.

Microcirculatory alterations in patients with severe sepsis: Impact of time of assessment and relationship with outcome. De Backer D, Donadello K, Sakr Y, Ospina-Tascon G, Salgado D, Scolletta S, Vincent JL., Crit Care Med. 2013 Mar;41(3):791-799. 

chronic care: wound healing

Prediction of wound healing outcome using skin perfusion pressure & transcutaneous oximetry.  Takkin Lo, MD, MPH, CWS, Richard Sample, BSPH, Patrick Moore, MBA, Philip Gold, MD., Wounds. 2009;21(11). 

The effect of LED on blood microcirculation during chronic wound healing in diabetic and non-diabetic patients-a prospective, double-blind randomized study. Frangez I, Cankar K, Ban Frangez H, Smrke DM., Lasers Med Sci. 2017 May;32(4):887-894. 

Assessment of microcirculation and the prediction of healing in diabetic foot ulcers. Jarrod Shapiro and Aksone Nouvong in Medicine » Endocrinology and Metabolism » "Topics in the Prevention, Treatment and Complications of Type 2 Diabetes", Chapter 11, edited by Mark B. Zimering, ISBN 978-953-307-590-7, Published: November 4, 2011 under CC BY 3.0 license. © The Author(s).

Pulsed electromagnetic field therapy promotes healing and microcirculation of chronic diabetic foot ulcers: a pilot study. Kwan RL, Wong WC, Yip SL, Chan KL, Zheng YP, Cheing GL. Adv Skin Wound Care. 2015 May;28(5):212-219.

The effects of intermittent negative pressure on the lower extremities’ peripheral circulation and wound healing in four patients with lower limb ischemia and hard-to-heal leg ulcers: a case report. Øyvind H. Sundby, Lars Ø. Høiseth, Iacob Mathiesen , Jørgen J. Jørgensen, Jon O. Sundhagen & Jonny Hisdal., Physiol Rep, 4 (20), 2016, e12998.

Chronic Disease: Cardiovascular  Disease-link with microcirculation

Skin microcirculation and echocardiographic and biochemical indices of left ventricular dysfunction in non-diabetic patients with heart failure. Dubiel M1, Królczyk J, Gąsowski J, Grodzicki T., Cardiol J. 2011;18(3):270-6.

Chronic Disease: Peripheral Arterial Disease-link with microcirculation

Relationship of lower extremity skin blood flow to the ankle brachial index in patients with peripheral arterial disease and normal volunteers. Otah KE1, Otah E, Clark LT, Salifu MO. Int J Cardiol. 2005 Aug 3;103(1):41-6. Epub 2005 Jan 28.